Thyroid cancer
Conditions
Interventions
This proposal improves values deliberation in treatment choices through development, implementation and evaluation of a multifaceted intervention (COMBO), that includes a decision aid, a values clarif
Sponsors
Radboudumc
Eligibility
Inclusion criteria
Inclusion criteria: Total thyroidectomy vs hemithyroidectomy: -patients with nodules >1 cm and <4 cm, with cytology result suspicious or malignant (Bethesda 5 or 6) with no clinical or radiological evidence of pathological lymph nodes and/or distant metastases before the primary (diagnostic) surgery -patients with histologically (after diagnostic hemithyroidectomy) proven TC but are defined as low-risk according to the ATA classification(97,98) -patients with multifocal TC -patients with incomplete resection of the primary tumor -patients with ATA defined intermediate risk or high risk No treatment with RAI vs. treatment with RAI: -patients with ATA defined low-risk (98) and patients with multifocal papillary TC in the absence of other adverse features. Active surveillance vs. systemic treatment: -patients with asymptomatic or mildly symptomatic RAI-refractory (slowly) progressive metastatic disease
Exclusion criteria
Exclusion criteria: Total thyroidectomy vs hemithyroidectomy: -patients with multifocal TC -patients with incomplete resection of the primary tumor -patients with ATA defined intermediate risk or high risk No treatment with RAI vs. treatment with RAI: -patients with ATA defined intermediate risk or high risk Active surveillance vs. systemic treatment: -patients with coexisting conditions that do not allow prescription of TKI’s
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Choice and decision making role Knowledge Evaluation of the decision Worries and trust Patient evaluation of SDM process Audio recording | — |
Primary
| Measure | Time frame |
|---|---|
| Quality of SDM, assessed from the audio-recording of the consultation. | — |
Contacts
Public ContactRosalie Koot
Radboudumc
Outcome results
None listed