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Brain changes as a consequence of blindness in one half of the visual field

Neuroplasticitiy in homonymous hemianopia: functional and structural brain changes underlying residual and compensatory perceptual behaviour

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON21100
Enrollment
40
Registered
2016-02-17
Start date
2016-03-01
Completion date
Unknown
Last updated
2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Homonymous hemianopia, post chiasmic cardiovascular accident Homonieme hemianopsia, post-chiasmatische beroerte

Interventions

auditory and visual functioning tests (f)MRI measurements

Sponsors

Prof. dr. N.M. Jansonius UMCG, Department of Ophthalmology HPC BB61, Postbus 30.001 9700 RB Groningen
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Participants with hemianopia: ­- have signed written consent ­- age older than 18 ­- homonymous hemianopia due to post chiasmic CVA ­ stable ophthalmologic conditions Controls: ­- have signed written consent ­ age older than 18 ­- subjectively healthy

Exclusion criteria

Exclusion criteria: Participants with hemianopia: ­- visual neglect ­- visual field defect due to condition other than post chiasmic CVA ­ clinical eye conditions ­- hearing impairments ­- macular sparing Controls: ­- visual impairments ­- auditory impairments

Design outcomes

Primary

MeasureTime frame
scores on visual and auditory functional tests, cortical activation and functional connectivity during visual and auditory processing, cortical and retinal nerve thickness and white matter tracts of all individual participants.

Secondary

MeasureTime frame
visual evoked potentials, outcomes of a standard questionnaire (to determine in-/exclusion), eye-tracking movements during visual tasks.

Contacts

Public ContactH.N. Halbertsma

NeuroImaging Center, room 124

h.n.halbertsma@umcg.nl+31 (0)50 363 4431

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)