Pituitary adenomas
Conditions
Interventions
Standard pituitary adenoma resection will be performed. Just before the actual resection, indocyanine green will be injected intravenously to identify the pituiraty adenoma using NIR fluorenscence.
Sponsors
Leiden University Medical Center (LUMC)
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients diagnoses with pitiutary adenoma, planned for resection; 2. Age between 18 and 80 years old.
Exclusion criteria
Exclusion criteria: 1. History of allergy to iodine, shellfish, indocyanine green or human serum albumin; 2. Pregnancy; 3. Hyperthyroidism; 4. Severe renal impairement; 5. Presence of any psychological, familial, sociological or geographical condition potentially hampering compliance with the study protocol and follow-up schedule; those conditions should be discussed with the patient before registration in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intra-operative identification rate, defined as the number of adenomas that were identified with the fluorescent signal of indocyanine green during operation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Tumor-to-background signal of the identified adenomas. | — |
Contacts
Public ContactC.J.H. Velde, van de
Leiden University Medical Center (LUMC), Department of Surgical Oncology, P.O. Box 9600
Outcome results
None listed