Muscle protein metabolism
Conditions
Interventions
Subjects will either consume 40 g plantbased or animal protein (isonitrogenous amount) in the form of a ready-to-eat product (n = 12 per group).
Sponsors
Maastricht University Medical Centre
Eligibility
Inclusion criteria
Inclusion criteria: • Males • Aged between 18 - 35 years • Healthy, recreationally active (max 3 days per week performing activities) • BMI 18.5 – 27.5 kg/m2
Exclusion criteria
Exclusion criteria: • Females • Diagnosed diabetes • Wheat allergy • Celiac disease • Smoking • Diagnosed metabolic or intestinal disorders • A history of neuromuscular problems • Any medications known to (or may) affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications). • Participation in structured resistance exercise program • Previous participation in a 13C amino acid tracer study within the last year
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary study parameters include myofibrillar protein synthesis rates, expressed as FSR (%/h), using muscle-protein bound L-[ring-13C6]-phenylalanine enrichments and muscle tissue-free and plasma L-[ring-13C6]-phenylalanine enrichments as precursor. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints will be plasma amino acid concentrations (total amino acid profile), glucose, and insulin concentrations. | — |
Contacts
Public ContactL.J.C. Loon, van
Capaciteitsgroep Human Biology, room 2.356, Universiteitssingel 50
Outcome results
None listed