Metabolic availability of L-lysine from milk powder using indicator amino acid oxidation technique

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON20970

Enrollment

Registered

2019-08-22

Start date

2019-10-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Digestion

Interventions

Two different milk powders

Eligibility

Inclusion criteria

Inclusion criteria: Adults: Apparently healthy adult male volunteers Normal Hb > 13g/l Age: 20-40 years Normal BMI between 18.5 to 25 kg/m2 Physical activity level <1.5 assess nu validated questionnaire Subject to agree to avoid smoking and alcohol consumption for the entire study duration Subject willing to participate and adhere to the study protocol for 7 consecutive weeks Children: Children 6-10 years of age, both sexes Apparently healthy BAZ between -2SD and 1 SD Children and parents willing to participate and adhere to adaptation diets for 5 consecutive weeks

Exclusion criteria

Exclusion criteria: Adults: History of smoking or taking other leisure drugs in past 3 months and/or study duration Consumption of alcohol in the previous 24 hr and/or in study duration History of antibiotics in last month On iron, protein, multivitamin, and/ or any other supplementation therapy in past 3 months Unstable weight over last 3 months Use of medications known to affect intestinal functions and protein metabolism Participation in any nutritional intervention study in last 3 months History of food allergy History of acute illness. gastointestinal, respiratory tract symptoms of fever in the past 1 week diagnosed with any acute or chronic medical conditions Children: Any acute or chronic illnesses Menarche Weight loss in last 1 month Worm infestation as assessed by stool test History of antibiotics in last month On iron, protein, multivitamin, and/ or any other supplementation therapy in past 3 months Use of medications known to affect intestinal functions and protein metabolism History of food allergy

Design outcomes

Primary

Measure	Time frame
Adults: true metabolic availability of L-lysine in two milk powders compared with a reference crystalline amino acid mixture Children: relative metabolic availability of L-lysine in two milk powders	—

Contacts

Public ContactIlse Tan-Khouw

FrieslandCampina

ilse.tan-khouw@frieslandcampina.com+65 65785921

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)