Chronic neuropathic pain - Chronische neuropatische pijn Spinal cord stimulation - Ruggermerg stimulatie EEG Evoked potentials (EP)
Conditions
Interventions
The patients are asked to turn off their stimulator 12 hours before the measurements and keep the stimulator turned off until the measurements are performed. For the control group there is no interven
Sponsors
Prof. M.J.A.M van Putten MD PhD
Clinical Neurophysiologist Medisch Spectrum Twente
t.: 053 487 2810
e-mail: m.vanputten@mst.nl
Eligibility
Inclusion criteria
Inclusion criteria: A patient group and a control group will be included. Patients: Patients who participated in a trial for a new form of stimulation (burst stimulation) and in whom EP and EEG measurements are performed during the case they still had classing (tonic) stimulation and during the case they had two week burst stimulation. Controls: Aged matched volunteers.
Exclusion criteria
Exclusion criteria: Patients: Hospitalisation or other form of serious decline of general health. Controls: Chronic pain, former brain surgery, diagnosed neurological disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The amplitudes of the reconstructed signal of the primary somatosensory cortex (S1) evoked by stimulation of Aβ-fibers and Aδ-fibers and pain scores, determined by a visual analog score (VAS). These amplitudes and pain scores will be compared in the tonic SCS, burst SCS, SCS off and controls. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondairy study parameters are the activity of other brain areas after Aβ and Aδ stimulation. In the rest EEG this activity is measured as power per frequency band. Other study parameters are the presence of allodynia, experience of paresthesias, pain scores per body part and quality of the pain (sharp, burning, etc.) | — |
Contacts
Public ContactC.C. Vos, de
Medisch Spectrum Twente, Department of Neurosurgery, P.O. Box 50000
Outcome results
None listed