Mechanical bowel preparation for elective colorectal surgery.

Mechanical bowel preparation for elective colorectal surgery. Outcome of a multicenter randomized study.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON20913

Enrollment

1433

Registered

2006-02-06

Start date

1998-04-15

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Patients were randomized before elective colorectal surgery to receive mechanical bowel preparation, consisted of 2-4 liters of polyethylene glycol bowel lavage solution in combination with a fliud di

Eligibility

Inclusion criteria

Inclusion criteria: Elective colorectal resections with primary anastomosis.

Exclusion criteria

Exclusion criteria: 1. Acute laparotomy; 2. laparoscopic colorectal surgery; 3. contraindications for the use of mechanical bowel preparation; 4. an a priori deviating (ileo) stoma; 5. age less than 18 years old.

Design outcomes

Primary

Measure	Time frame
The primary endpoint of the study was anastomotic failure, which was based on clinical suspicion (prolonged fever, abdominal pain, local or generalized peritonitis, leucocytosis) resulting in contrast radiography (X-ray or CT-scan) or laparotomy to confirm the diagnosis. No effort was made to screen for asymptomatic leakage.	—

Secondary

Measure	Time frame
Secondary endpoints were septic complications (wound infection, urinary tract infection, pneumonia, pelvic abscesses), fascia dehiscence and death.	—

Contacts

Public ContactCaroline Contant

Fransiscus Gasthuis, Department of Surgery, Kleiweg 500

vbrusselcontant@cs.com

Outcome results