Dyspepsia - Buspiron.

Does buspiron induce a raised prolactin response in functional dyspeptics?

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON20895

Enrollment

Registered

2005-05-31

Start date

2005-06-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Single dose of Buspiron (30 mg).

Eligibility

Inclusion criteria

Inclusion criteria: Healthy volunteers: absence of gastrointestinal symptoms, Nepean Dyspepsia Index (NDI) score 18 years of age. Patients: Nepean Dyspepsia Index (NDI) score >25, > 18 years of age.

Exclusion criteria

Exclusion criteria: Healthy volunteers: use of drugs that affect gastrointestinal motility (antidepressants, opiates, NSAID’s, calcium-blockers, nitrates), previous abdominal surgery, epilepsy, severe liver of renal insufficience, depression, claustrophobia, metal implants, not be able to lie down for 15 minutes. Patients: use of drugs that affect gastrointestinal motility (antidepressants, opiates, NSAID’s, calcium-blockers, nitrates), IBS, previous abdominal surgery, epilepsy, severe liver of renal insufficience, depression, claustrophobia, metal implants, not be able to lie down for 15 minutes.

Contacts

Public ContactG.E.E. Boeckxstaens

Academic Medical Center (AMC), Department of Gastroenterology, C2-328, P.O. Box 22660

g.e.boeckxstaens@amc.uva.nl+31 (0)20 5667375

Outcome results