Postoperative Cognitive Dysfunction (POCD)
Conditions
Interventions
None listed
Sponsors
Amsterdam UMC, location AMC - Department of Anesthesiology
Eligibility
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this study, a patient must meet all of the following criteria: - Elective minor, moderate or major surgery, according to the definition of the European Society of Anesthesiology - Age =65 years - ASA l - lV - Fluent in written and spoken Dutch - Willing and able to undergo neuropsychological assessment, and have the MoCA and TICS administered both pre- and approximately one month postoperatively.
Exclusion criteria
Exclusion criteria: Exclusion criteria: - Emergency surgery - Previously diagnosed cognitive dysfunction - Patients who are unable to understand or fill-in questionnaires in Dutch
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| -Agreement between performance on the TICS, MoCA and NPA and its cognitive domains oThe correlation between the TICS, MoCA and total NPA score and baseline characteristics oThe correlation between the TICS, MoCA and the cognitive domain scores of the NPA and baseline characteristics oThe correlation between TICS and MoCA total scores and cognitive domain scores pre- and approximately one month postoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| - The validity, sensitivity and specificity of the TICS and MoCA questionnaires compared to the gold standard (NPA) both on baseline and on postoperative change scores from baseline | — |
Contacts
Public ContactMark van Zuylen
Amsterdam UMC, location AMC
Outcome results
None listed