Blood flow measurement with MRI in the large vessel around the heart (aorta and pulmonary artery) show a measurement error
Conditions
Interventions
Observational study.
Seperate phantom measurements will be obtained after an in vivo clinical MRI scan.
Sponsors
VU University Medical Center
Eligibility
Inclusion criteria
Inclusion criteria: - Informed consent - Sinus rhythm at CMR examination - 2D flow acquisitions by MRI at the aorta or pulmonary artery without spatial infolding artefacts. - MRI acquisition on MRI system by Siemens: Magnetom Avanto, VB17 or newer 1.5 T systems such; for GE: Signa Excite (HDx 15M4) or newer as the Optima MR360; and for Philips: Achieva R2.6.3 or newer as the Ingenia. - MRI flow acquisitions with the general accepted standard settings
Exclusion criteria
Exclusion criteria: - Incapacitated adults. - Lack of a phantom measurement within the protocol specifications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary study outcome parameter is the velocity offset in cm/s at the location of the aorta or pulmonary artery. | — |
Secondary
| Measure | Time frame |
|---|---|
| - To describe the offset error over the systems included in the study - To test whether the static phantom offset corrections are valid, the difference between the velocity at the thorax wall and the phantom be assessed. - The validity of offset corrections using higher order fitting, and the LPC filter. | — |
Contacts
Public ContactM.B.M. Hofman
dept. Physics & Medical Technology VU University Medical Center P.O. Box 7057, 1007 MB Amsterdam, the Netherlands
Outcome results
None listed