Conditions required ventilator support in the Intensive Care Unit
Conditions
Interventions
None listed
Sponsors
Maastricht UMC
Eligibility
Inclusion criteria
Inclusion criteria: Any patient admitted to the intensive care unit must meet all of the following criteria to be eligible for the PRECISe study: 1. Adult = 18 years-old admitted to the ICU 2. Unplanned ICU admission 3. Invasive mechanical ventilation initiated <24 hours of ICU admission 4. Expected ICU stay on ventilator support of = 3 days
Exclusion criteria
Exclusion criteria: Any patient admitted to the Intensive Care Unit meeting one or more of the following criteria is not eligible for the PRECISe study: 1. Contraindication for enteral nutrition 2. Moribund or expected withholding of treatment 3. Kidney failure with “no dialysis”-code on admission 4. Hepatic encephalopathy (West Haven 3 – 4) 5. Body-mass index 0.7 for 24 hours after admission. 2. Positive end-expiratory pressure (PEEP) expected to remain > 12 cm H2O for 24 hours after admission. 3. Patient is on ECMO the first 24h after admission
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the course of resting energy expenditure (REE), measured by indirect calorimetry, during ICU stay (and after that until hospital discharge, when feasible), between patients fed with high versus standard enteral protein within the PRECISe trial. | — |
Secondary
| Measure | Time frame |
|---|---|
| To associate course of REE with physical performance, using the MRC sum-score at ICU-discharge, hospital discharge and at 1-month follow-up. | — |
Contacts
Public ContactJonathan Huising
Ziekenhuis Gelderse Vallei, Ede
Outcome results
None listed