diabetes type 2
Conditions
Interventions
Patients will receive either 5 gram of Sargassum fusiforme (Sargassum), 5 gram of Fucus vesiculosus (Fucus) or placebo (0.5 gram Nori) during 5 weeks (week 2-6).
Sponsors
Erasmus Medical Center
Eligibility
Inclusion criteria
Inclusion criteria: - Patients with T2DM and BMI>25 - All adults; age = 18 years - Diabetes based on criteria of ADA
Exclusion criteria
Exclusion criteria: - Type 1 or monogenetic forms of diabetes. - Thyroid disease - Pregnancy - Usage of corticosteroids - Usage of blood anti-coagulants - History of heart failure or recent myocardial infarction within 3 months - Transplantation - Allergy for shellfish
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference between the mean blood glucose levels measured during the first week of usual diet and during week 2 to 6 when daily seaweed is consumed. | — |
Secondary
| Measure | Time frame |
|---|---|
| differences between week 1 and week 6 in terms of body weight (kg); HbA1c and total daily insulin use, and fasting blood glucose levels (Mmol/L) in addition to the continuously monitored glucose levels. Levels of total cholesterol, LDL-cholesterol, HDL-cholesterol, lipoprotein (a) (g/L), apoB100/48 (Mmol/L) and triglycerides (Mmol/L) (measured using routine laboratory analysis) will be analyzed, and pulse wave velocity and blood pressure (mmHg) and cytokines. | — |
Contacts
Public ContactKirsten Berk
Erasmus MC
Outcome results
None listed