Post-operative hemorrhagic complications and thrombo-embolic complications after neurosurgical spinal surgeries in patients using aspirin anti-thrombotic medication.
Conditions
Interventions
Current practice guidelines recommend the discontinuation of aspirin 5 days pre-operatively until at least 3 days post-operatively. The intervention in the Aspin-study is to observe the rate of hemorh
Sponsors
Haaglanden medical center.
Eligibility
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this study, a subject must meet all of the following criteria: • Scheduled spinal surgery • Preoperative use of aspirin • Age >18
Exclusion criteria
Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study: • Surgery with high risk for hemorrhage such as tumors requiring preoperative embolization • Staged surgeries lasting more than one day • Patients with a pre-existing coagulopathy • Patients using antithrombotic drugs or other platelet aggregation inhibitors than aspirin • Patients with absolute contraindication for discontinuing aspirin (e.g. coronary stenting within 1 year) • Patients aged under 18 • Emergency surgical procedures
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primay outcome measures include perioperative blood loss, hemorrhage related complications and need for reoperation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome is the reduction of cardiac and neurologic thrombotic perioperative events within 30 days after surgery. | — |
Contacts
Public ContactAhmed Zian
Haaglanden medisch centrum, afdeling Neurochirurgie
Outcome results
None listed