Investigation on the effect of shear loading on skin, with application to early detection of skin damage

Investigation on the effect of shear loading on cytokine release of human skin

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON20734

Enrollment

Registered

2017-04-20

Start date

2017-06-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pressure ulcers Decubitus Doorligwonden

Interventions

A varying shear load is applied for 1 hour, which is repeated for three sessions. Before and after application of the shear load, a sebutape is applied to absorb the sebum which is present on top of t

Eligibility

Inclusion criteria

Inclusion criteria: Age between 18 and 35 Healthy Braden score > 20 BMI between 20 and 30 kg/m2

Exclusion criteria

Exclusion criteria: Any history of skin diseases Trauma at the volar aspect of the forearms Known diseases such as: heart diseases, respiratory diseases, diabetes, other diseases to microcirculation, skin diseases, sensory diseases, muscle diseases Pregnancy Unable to sit still for 1 hour

Design outcomes

Primary

Measure	Time frame
Primary outcome is the IL-1a concentration in the sebum layer. This concentration is used as biomarker for early detection of pressure ulcers.	—

Secondary

Measure	Time frame
Not applicable.	—

Contacts

Public ContactM. Klaassen

Building Horst - Room N114

m.klaassen@utwente.nl0534896883

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)