ETMI vs. standard video endoscopy for the detection of early neoplasia in patients with low-grade dysplasia in a Barrett's esophagus: a multi-center randomized cross-over controlled study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON20674

Enrollment

Registered

2007-01-08

Start date

2007-01-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Barrett's esophagus

Interventions

ETMI-gastroscopy and standard video gastroscopy

Eligibility

Inclusion criteria

Inclusion criteria: 1. Barrett's esophagus patients with low-grade dyplasia comfirmed by two expert GI pathologists; 2. Written informed consent

Exclusion criteria

Exclusion criteria: 1. Presence of active erosive esophagitis grade A according to the Los Angles classification of erosive esophagitis; 2. Presence of conditions precluding histological sampling of the esophagus (e.g. esophageal varices, coagulation disorders, anticoagulant therapy); 3. < 18 years

Design outcomes

Primary

Measure	Time frame
1. Number of patients with early neoplasia detected with ETMI or SVE; 2. Number of lesions with early neoplasia detected with ETMI and SVE.	—

Secondary

Measure	Time frame
1. Number of early neoplastic lesions detected with AFI only; 2. Reduction of false positives findings after detailed NBI evaluation.	—

Contacts

Public ContactJ.J.G.H.M. Bergman

Academic Medical Center Bldg. C2-210, Meibergdreef

j.j.bergman@amc.uva.nl+31 (0)20 5669111

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)