Sarcopenia
Conditions
Interventions
Subjects will be randomly assigned to consume either a drink containing isolated casein or casein in the normal milk matrix. By the use of stable isotope methodology we will assess the digestion and a
Sponsors
Maastricht University
Eligibility
Inclusion criteria
Inclusion criteria: - Males - Aged between 65-85 years - Healthy, recreationally active - BMI < 30 kg/m2
Exclusion criteria
Exclusion criteria: - Female - Smoking - Allergies to milk proteins (whey or casein) - Arthritic conditions - Over the counter antacids - Diabetes mellitus type 1 and type 2 - A history of neuromuscular problems - Individuals on any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications). - Participation in any regular exercise program - Chronic use of gastric acid suppressing medication or anti-coagulants - Unstable weight over the last three months - Pathologies of the gastrointestinal tract
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fractional synthetic rate | — |
Secondary
| Measure | Time frame |
|---|---|
| • Exogenous phenylalanine rate of appearance and plasma availability of phenylalanine. • Total rate of phenylalanine appearance and disappearance • Endogenous phenylalanine rate of appearance | — |
Contacts
Public ContactL.J.C. Loon, van
Capaciteitsgroep Human Biology, room 2.356, Universiteitssingel 50
Outcome results
None listed