Bone mineral density changes in the knee after meniscal allograft transplantation. A 2-year follow-up.

Bone mineral density changes in the knee two years after meniscal allograft transplantation

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON20552

Enrollment

Registered

2015-12-24

Start date

2010-03-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

A potential chondroprotective effect of meniscal allograft transplantation (MAT) remains still unclear. Subchondral bone mineral density (BMD) and subchondral bone remodelling play important roles in the development of osteoarthritis. The purpose of our study was to determine BMD changes after MAT during a 2 year follow-up. BMD changes between the operated and the non-operated knee, as well as correlation between BMD, bone scintigraphy and Knee injury and Osteoarthritis Outcome Score (KOOS) were

Interventions

Knee injury and Osteoarthritis Outcome Score (KOOS) preopertive and postoperative after 6 months, 1 year and 2 year Preoperatively and 6 months, 1 year and 2 years postoperative, a DXA scan and a bon

Eligibility

Inclusion criteria

Inclusion criteria: disabling unicompartmental pain after a (sub)total meniscectomy, patient under the age of 55 years, stable knee joint or stabilized by concomitant ACL reconstruction (ACLR) and normal knee alignment.

Exclusion criteria

Exclusion criteria: grade IV chondropathy, PCL insufficiency, abnormal and uncorrected knee or lower limb alignment, chronic pain syndrome of the knee, arthrofibrosis, muscular atrophy and a history of knee sepsis.

Design outcomes

Primary

Measure	Time frame
Bone mineral density, semi-quantitatively bone scan scores	—

Secondary

Measure	Time frame
Knee injury and Osteoarthritis Outcome Score (KOOS)	—

Contacts

Public ContactB.J.W. Thomassen

Haaglanden Medical Center PO Box 432

b.thomassen@mchaaglanden.nl+31 (0)70 3303109

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)