Is the use of bloodplatelets effective in the treatment of difficult fistulas related to the anal sfincter?

Use of platelet rich plasma as an adjunct in the treatment of high peri-anal fistulas.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON20536

Enrollment

120

Registered

2011-03-24

Start date

2011-04-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

platelet rich plasma, peri-anal fistulas trombocytenrijk plasma, peri-anale fistels

Interventions

This study consists of two arms. One arm will be treated conventionally with a mucosa advancement flap, with a seton procedure in advance. The other arm will be treated with a mucosa advancement fla

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age 18-80 years; 2. Able to understand informed consent; 3. Complex peri-anal fistula.

Exclusion criteria

Exclusion criteria: 1. Pregnancy; 2. Local malignancy; 3. Crohn's disease/ulcerative colitis; 4. A traumatic or iatrogenic lesion; 5. Trombocytopenia; 6. Splenomegaly; 7. Bleeding disorders; 8. Hematologic malignancies.

Design outcomes

Primary

Measure	Time frame
Recurrent fistulas. The surgeon or docter in the outpatient clinic will decide if there is a recurrent fistula or not. In case of doubt a MRI will be made.	—

Secondary

Measure	Time frame
1. Visual analogue scale (VAS-score); 2. Quality of life (SF-36 questionnare); 3. Incontinence (Vaizey score).	—

Contacts

Public ContactR. Wouda

rosannewouda@gmail.com0613232756

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)