Analyzes of pathogen and host determinants in hospitalized patients with a laboratory confirmed infection caused by Staphylococcus aureus: the PATHOS Study.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON20533

Enrollment

Registered

2007-08-13

Start date

2007-11-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

English: Staphylococcus aureus, vaccine, antigen, determinant Dutch: Staphylococcus aureus, vaccin, antigeen, determinant

Interventions

Blood will be drawn at days 2, 7 and 14 after the moment that the initial blood and wound cultures were obtained. This will be done simultaneously to drawing blood for routine haematology and chemistr

Eligibility

Inclusion criteria

Inclusion criteria: 1. Adult patients (>18 years) with S. aureus bateraemia or wound infection; 2. Diagnosis of S. aureus infection within 48 hours after initial cultures; 3. Informed consent.

Exclusion criteria

Exclusion criteria: 1. Incapacitated patients (GSC<15); 2. Patients with neutropenia (< 500x 10e6 neutrophils/L); 3. Patients with haematological malignancy; 4. Transplantation patients; 5. Patients who are treated with immunsuppressive drugs.

Design outcomes

Primary

Measure	Time frame
Putative antigen targets for the development of a Staphylococcus aureus vaccine.	—

Contacts

Public ContactJ.A.J.W. Kluytmans

VU University Medical Center Department of Medical Microbiology & Infection Control P.O. Box 7057

jan.kluytmans@vumc.nl+31 20-4440552

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)