Early treatment of central serous retinopathy by photodynamic therapy. A randomized controlled trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON20530

Enrollment

Registered

2010-03-26

Start date

2010-04-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Central serous retinopathy.

Interventions

Photodynamic therapy (PDT) versus observation. In the observational arm, patients with persistent lesions at 3 months will be treated with PDT in agreement with current standard of care. PDT: Visudyn

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age > 18 years; 2. Informed consent; 3. Poor prognositic acute CSR.

Exclusion criteria

Exclusion criteria: 1. History of CSR in either eye; 2. Allergy to fluorescein dyes; 3. Allergy to visudyne; 4. Opaque ocular media, impairing regular fundus imaging; 5. Other ocular disorder possibly reducing visual acuity.

Design outcomes

Primary

Measure	Time frame
Visual acuity at 1 year (ETDRS letter cart).	—

Secondary

Measure	Time frame
1. Metamorphopsia (Amsier cart); 2. Color vision (Hardy Rand Ritter colortest); 3. Recurrence (Optical Coherence Tomographt); 4. Presence of persistent subretinal fluid on OCT; 5. Lesion size on autofluorescence imaging (OCT).	—

Contacts

Public ContactT. Missotten

Oogziekenhuis Rotterdam, Schiedamsevest 180,

t.missotten@oogziekenhuis.nl010 401777

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)