None listed
Conditions
Interventions
Subjects use their own refillable e-cigarette for the home-use test with the study e-liquids. The type of e-cigarette is registered by the Essensor researcher. The settings of the e-cigarette can be c
Sponsors
RIVM
Eligibility
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this study, a subject must meet all of the following criteria: - Aged 18 to 70 years at the time of inclusion - Vaping at least more than once per week - Used to vape e-liquids with nicotine (>1 mg) - Generally healthy as self-reported - Owning and using a refillable e-cigarette - Owning and familiar with using a computer (with webcam and microphone)
Exclusion criteria
Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study: - Women only: pregnant or lactating - Experiences negative health effects of vaping or smoking - Asthma or other lung disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Perceived liking, nicotine intensity (buzz), harshness/throat hit, pleasantness of throat hit, and willingness to use again (on a 100-unit VAS scale) for nicotine free-base and nicotine salts e-liquids. Puffing intensity (average puff number, puff duration and time between puffs for nicotine free-base and nicotine salts e-liquids. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Gender, smoking status (dual use), liquid order and used to nicotine salts. - Difference in liking, nicotine intensity (buzz), harshness/throat hit, pleasantness of throat hit over time (after 5 min versus after 10 min). - Correlation coefficients between liking, intensity, harshness/throat hit, pleasantness of throat hit, and nicotine buzz. | — |
Contacts
Public ContactCharlotte Pauwels
RIVM
Outcome results
None listed