Taste function after chorda tympani injury

The impact of injury of the chorda tympani nerve during primary stapes surgery and primary cochlear implantation on taste function, quality of life and food preferences

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON20460

Enrollment

154

Registered

2021-10-13

Start date

2021-10-18

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

loss of taste function

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: • Signed Informed Consent form • Age = 18 years • Scheduled or on the waiting list of primary stapes surgery or primary cochlear implantation • Willingness and ability to participate in all scheduled procedures outlined in the study protocol • Good understanding of the Dutch language

Exclusion criteria

Exclusion criteria: • Previous middle ear surgery (with the exception of the placement of ventilation tubes in childhood) • Disability that could interfere with taste evaluation and/or questionnaire fulfilment • History of chemotherapy and/or radiotherapy • History of facial nerve palsy • Cardiac pacemaker • Pregnancy • History of orofacial pain • History of dysesthesia in the orofacial region • Local evidence of a pathological condition of the oral mucosa

Design outcomes

Primary

Measure	Time frame
To evaluate the prognostic effect of CTN injury on postoperative taste function measured using taste strips in patients undergoing primary stapes surgery or primary cochlear implantation.	—

Secondary

Measure	Time frame
• To compare the postoperative EGM threshold in uA for different locations of the tongue in patients between two types of CTN injury (stretching or sacrificing) • To compare the presence of postoperative symptoms of taste disturbance in patients between two types of CTN injury (stretching or sacrificing). • To compare the postoperative perception of appetite, hunger and sensory in patients between two types of CTN injury (stretching or sacrificing). • To compare the postoperative quality of life in patients between two types of CTN injury (stretching or sacrificing). • To compare the postoperative enjoyment of food in patients between two types of CTN injury (stretching or sacrificing). • To compare the postoperative food preference in patients between two types of CTN injury (stretching or sacrificing). • To compare the postoperative odour identification score in patients between two types of CTN injury (stretching or sacrificing)	—

Measure

Time frame

• To compare the postoperative EGM threshold in uA for different locations of the tongue in patients between two types of CTN injury (stretching or sacrificing) • To compare the presence of postoperative symptoms of taste disturbance in patients between two types of CTN injury (stretching or sacrificing). • To compare the postoperative perception of appetite, hunger and sensory in patients between two types of CTN injury (stretching or sacrificing). • To compare the postoperative quality of life in patients between two types of CTN injury (stretching or sacrificing). • To compare the postoperative enjoyment of food in patients between two types of CTN injury (stretching or sacrificing). • To compare the postoperative food preference in patients between two types of CTN injury (stretching or sacrificing). • To compare the postoperative odour identification score in patients between two types of CTN injury (stretching or sacrificing)

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Contacts

Public ContactEsther Blijleven

UMC Utrecht

e.e.blijleven-2@umcutrecht.nl+31 88 75 694 75

Outcome results