Pain perception of the skin in healthy volunteers and neuropathic pain patients

Sensory testing of the skin using heat stimulation in healthy volunteers and neuropathic pain patients

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON20446

Enrollment

Registered

2013-06-05

Start date

2013-03-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Pain measurement. The Visual Analogue Scale (VAS) will be used to quantify pain intensity in response to a noxious thermal stimulus. The thermal stimulus will be applied on the volar side of the forea

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with CRPS-1, small-fiber neuropathy, central neuropathic pain or fibromyalgia, according to the guidelines of the IASP or other professional pain societies (eg., Netherlands Society of Anesthesiologists); 2. A pain score of 5 or higher; (iii) age between 18 and 75 years; (iv) being able to give written informed consent. Volunteer inclusion criteria. Healthy volunteers in the age range 18-75 years of either sex.

Exclusion criteria

Exclusion criteria: 1. Unable to give written informed consent; 2. Medical disease such as renal, liver, cardiac, vascular (incl. hypertension) infectious disease; 3. Increased intracranial pressure; 4. Epilepsy; 5. Psychosis; 6. Glaucoma; 7. A history of cerebro-vascular accident 30).

Design outcomes

Primary

Measure	Time frame
Response to different kind of pain stimuli	—

Contacts

Public ContactAlbert Dahan

Leiden University Medical Center (LUMC), Department of Anesthesiology, P.O. Box 9600

a.dahan@lumc.nl+31 (0)71 5262301

Outcome results