The use of helium after cardiac arrest.

The use of helium after resuscitation: a safety and feasibility study.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON20392

Enrollment

Registered

2010-03-24

Start date

2010-04-06

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac arrest (hartstilstand) Resuscitation (reanimatie) Postanoxic coma (postanoxisch coma) Helium (helium)

Interventions

Ventilation with helium/oxygen (50%/50%) during the first 3 hours after inclusion.

Eligibility

Inclusion criteria

Inclusion criteria: 1. Admission to the ICU with postanoxic coma after OHCA; 2. First registered rhythm VF/VT; 3. Witnessed arrest; 4. Return of spontaneous circulation within 30 minutes; 5. Induced mild hypothermia; 6. Ability to start study medication within 6 hours.

Exclusion criteria

Exclusion criteria: 1. Life expectancy 50% FiO2 and > 10 cmH2O PEEP.

Design outcomes

Primary

Measure	Time frame
Occurence of major adverse events (death, inability to effectivly ventilate using helium/oxygen).	—

Secondary

Measure	Time frame
1. Arterial blood gas; 2. Ventilator settings; 3. Creatine Kinase; 4. Creatine Kinase MB; 5. Troponin-T; 6. Neuro Specific Enolase; 7. Glassgow Outcome Score; 8. Mortality; 9. Duration of mechanical ventilation; 10. Length of stay on ICU.	—

Contacts

Public ContactDaniel Brevoord

Postbus 22660, M0-126

d.brevoord@amc.nl+31 (0)20 5669111

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)