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How we evaluate our food: Mapping brain regions involved in evaluating calories, taste intensity and pleasantness

How we evaluate our food: Mapping brain regions involved in evaluating calories, taste intensity and pleasantness

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON20294
Enrollment
26
Registered
2015-06-16
Start date
2015-06-24
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Selective attention, evaluation of foods, calories, taste intensity, pleasantness

Interventions

Participants are instructed to pay attention to either the calories, taste intensity or pleasantness of a sweet, a savory and a neutral stimulus and accordingly taste these stimuli.

Sponsors

Wageningen University
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: • Age: 18-35 years • BMI: 18.5 – 25.0 kg/m2 • Healthy (as judged by the participant) • Being right handed • Willing to comply with the study procedures • Willing to be informed about incidental findings of pathology • Having given written informed consent • Successful completion of the training session

Exclusion criteria

Exclusion criteria: • Restraint eating (women: score > 2.80) • Lack of appetite • Having difficulties with tasting, smelling, swallowing or eating • Usage of an energy restricted diet during the last two months (preceding the screening session) • Weight loss or weight gain of 5 kg or more during two months (preceding the screening session) • Stomach or bowel diseases • Diabetes, thyroid disease, kidney disease and other chronical disorders • Having epilepsy or other neurological disorders • Having claustrophobia, schizophrenia or another mental illness • Usage of daily medication other than oral contraceptives, paracetamol or H1-antihistaminergic drugs • Pregnancy during the last 6 months, having the intention to become pregnant or lactating • Smoking on average more than one cigarette/cigar a day • Being allergic/intolerant for products under study • Disliking the beverages under study • Working or doing an internship/thesis at the Department of Human Nutrition (WUR) • Current participation in other (medical) research (except the EetMeetWeet study) • Having a history of or current alcohol consumption of on average more than 21 units per week • Having objections against being informed about incidental findings of pathology and against the general physician being informed about incidental findings of pathology • Having a contra-indication to MRI scanning (including, but not limited to):  Pacemakers and defibrillators  Intraorbital or intraocular metallic fragments  Ferromagnetic implants  Presence of non-removable metal objects in the mouth  Presence of non-removable piercings  Presence of tattoos with iron pigments

Design outcomes

Primary

MeasureTime frame
The main study parameter/endpoint is brain activation during tasting.

Secondary

MeasureTime frame
The secondary parameter/endpoint is ad libitum food intake.

Contacts

Public ContactInge Rijn, van

Bomenweg 2

inge.vanrijn@wur.nl+31 (0)317 480759

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)