Depression
Conditions
Interventions
Besides usual care, patients in the intervention group will be enrolled in a six months supervised, group physical activity program (running therapy or Nordic walking). In total 40 sessions (twice a w
Sponsors
Symfora groep
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age between 18-65; 2. Diagnoses of unipolar depression, or bipolar depression, or seasonal depression not responding to light therapy (10 sessions of 1 hour) (using DSM-IV criteria); 3. Baseline Hamilton Rating Scale of Depression (HRSD) score of 14 or higher; 4. (Will be) treated for depression.
Exclusion criteria
Exclusion criteria: 1. Patients with comorbid disorders (including depression due to another comorbid condition, psychotic disorder, schizophrenia, schizoaffective disorder or obsessive compulsive disorder, anxiety disorder as primary diagnosis); 2. Patients in longstay facilities (including day care) or with complex pathology, treatment resistant depression and multiple hospital admissions with little effect on the depressive state; 3. Significant cardiovascular disease or other medical conditions which contra-indicates exercise therapy; 4. Contraindications for walking and/or running; 5. Pregnancy; 6. Addiction to alcohol and other drugs as a primary diagnosis (DSM-IV criteria Substance Depence); 7. High suicide risk; 8. Regular physical exercise (2-3 times a week on a high-intensity).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depression symptoms (the Hamilton Rating Scale for Depression). Timepoints: 6 and 12 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Metabolic syndrome: length/weight2 (BMI), waist circumference, systolic and diastolic blood pressure, fasting glucose, triglycerides, total cholesterol, HDL-cholesterol, cholesterol/HDL-ratio, creatinine and Cockroft clearance. Timepoint: 6 and 12 months; 2. Quality of Life (WHO-DAS) at 6 and 12 months; 3. Cost effectiveness (TIC-P, Euroqol, subjective health, VAS) at 6 and 12 months. | — |
Contacts
Public ContactFrank Kruisdijk
Postbus 3015
Outcome results
None listed