prostate carcinoma
Conditions
Interventions
The study is a radiotherapy pilot planning study simulating the MR based RT dose on the daily MRI-anatomy. Patients treated by standard EBRT in 5 fractions within Radiotherapiegroep (RTG) (Deventer, t
Sponsors
Radiotherapiegroep
Eligibility
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this study, a subject must meet all of the following criteria: • Patients with a low to intermediate risk localized PCa confirmed by biopsy and scheduled for curative intent EBRT at RTG; • = 18 years; • No transurethral resection of the prostate (TURP) in the last 3 months; • No anorectal surgery in the past or other situations in which the anorectal anatomy is abnormal; • No hip prosthesis; • Meet all MRI safety criteria for MRI at 1.5T according to the protocol of the department of Radiology; • Written informed consent.
Exclusion criteria
Exclusion criteria: • V18 years; • Transurethral resection of the prostate (TURP) in the last 3 months; • Anorectal surgery in the past or other situations in which the anorectal anatomy is abnormal; • Hip prosthesis; • No compliance with all MRI safety criteria for MRI at 1.5T according to the protocol of the department of Radiology; • No written informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| oD2cc of the rectum (the minimum dose in 2cc of the rectum receiving the highest dose) and the mean difference in D2cc between the traditional and the online adaptive protocol. oD2cc of the bladder (the minimum dose in 2cc of the bladder receiving the highest dose) and the mean difference in D2cc between the traditional and the online adaptive protocol. | — |
Secondary
| Measure | Time frame |
|---|---|
| o D99% and D95% CTV prostate o D50% of the rectum and bladder o Dmean of the anal canal o D2cc of the small bowel Dx% is the minimum dose to the highest irradiated x% volume of the volume of interest. | — |
Contacts
Public ContactDorien Haverkort
Radiotherapiegroep
Outcome results
None listed