Depression.
Conditions
Interventions
Patients were randomly assigned to four sessions of counselling during 3 months with (n=85) or without paroxetine (n=96). Both treatments were carried out by the patient’s own GP.
Sponsors
VU University Medical Centre
EMGO-Institute
Dept. General Practice
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 18 years or over; 2. Having 3-6 out of 9 depressive symptoms for at least 2 weeks for most days of the week, including at least one of the core symptoms ‘sadness’ or ‘loss of pleasure’; 3. Impairment by depressive symptoms in social, occupational or other important areas of functioning. (minor depression=3-4 symptoms, mild-major depression=5-6 symptoms).
Exclusion criteria
Exclusion criteria: 1. Current intake of antidepressants or receiving psychological therapy; 2. Psychotic features; 3. Alcohol or drug addiction; Z 4. Loss of a loved one or significant other in the past six months; 5. Pregnancy or breastfeeding; 6. Inability to complete questionnaires because of language difficulties, illiteracy or cognitive decline; 7. Not having a telephone.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Severity of Depressive by MADRS (Montgomery Åsberg Depression Rating Scale); 2. Remission of depression by MADRS score<10. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Quality of Live (Short Form 36); 2. Subjective deprssion (Beck Depr. Inventory); 3. Client Satisfaction Questionnaire; 4. Direct and indirect costs. | — |
Contacts
Public ContactHein Hout, van
VU University Medical Center, EMGO-Institute, Van der Boechorststraat 7
Outcome results
None listed