Colorectal cancer
Conditions
Interventions
1. Diffusion-weighted whole-body imaging with background body signal suppression (DWIBS)
2. Colonoscopy.
Sponsors
University medical center, Utrecht, The Netherlands
Prof. dr. Siersema, MD, PhD
Department of Gastroenterology and Hepatology
University Medical Center Utrecht
P.O. Box 85500, 3508 GA Utrecht
Heidelberglaan 100, 3584 CX Utrecht
Tel.nr.: +31 88 7555555
Fax.nr.: +31 88 755 5533
E-mail: p.d.siersema@umcutrecht.nl
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 50 years or older; 2. Patients who will undergo a colonoscopy because of the suspicion of having colorectal carcinoma, with at least one of the following symptoms: rectal blood loss, altered bowel habits, unexplained weight loss, abdominal pain, and/or anemia; 3. Written informed consent.
Exclusion criteria
Exclusion criteria: 1. General contra-indications for MRI (metal devices [pacemakers, endoprotheses, intra uterine devices, neurostimulators, insulin pump, intra-ocular parts of metal, ear implants, artificial metal cardial valves], claustrophobia); 2. Weight >100kg; 3. A history of another malignancy; 4. Pregnant patients or patients lactating; 5. Patients in which therapy is already started.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Investigate whether DWIBS is effective for colorectal cancer screening. | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensitivity of DWIBS for the detection of colorectal cancer and polyps > 6mm. | — |
Contacts
Public ContactA. Leufkens
University Medical Center Utrecht P.O. Box 85500
Outcome results
None listed