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Endo-Epi mapping of CFAE.

Simultaneous Endocardial and Epicardial Mapping of Electrical Activity during Atrial Fibrillation to Study the Occurrence and Origin of Complex Fractionated Atrial Electrograms.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON20144
Enrollment
48
Registered
2011-04-07
Start date
2011-06-01
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial Fibrillation

Interventions

1. To apply a high density mapping catheter (64 poles) on the epicardial side of the atrium, facing the endocardial catheter routinely used for electrophysiological exploration of AF
2. To compare offline the corresponding tracings.

Sponsors

University of Maastricht Maastricht Universityhospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients who have signed an informed consent and who are admitted for RF ablation of AF in the "hybrid Operating Room" (HOR). Ablation of AF in HOR require an endocardial and epicardial approach through thoracoscopy, allowing concommittant access to endo and epicardial side of the atrial wall

Exclusion criteria

Exclusion criteria: 1. Patients that didn't give their consent; 2. Patients that don't speak Dutch; 3. Patients that are not will competent.

Design outcomes

Primary

MeasureTime frame
1. To demonstrate endo-epicardial electrical dissociation (EED) in human atrial fibrillation by recording simultaneously endocardial and epicardial surface; 2. To study epicardial conduction pattern in areas overlaying endocardial CFAE’s.

Secondary

MeasureTime frame
1. To study the relationship between EED and CFAE’s; 2. To study the difference in occurrence of EED and CFAE’s between patients with paroxysmal AF (PAF-group) and patients with persistent/longstanding persistent AF (AF-group); 3. To discriminate different types of CFAE and identify those who most likely contribute to AF perpetuation.

Contacts

Public ContactMathieu Granier

P.O. Box 616

mathieu.granier@maastrichtuniversity.nl+31 (0)43 3881200

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)