Misoprostol in the management of retained placenta, a safe alternative for manual removal? A randomised controlled trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON20129

Enrollment

100

Registered

2007-06-25

Start date

2007-08-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Retained placenta

Interventions

In case of retained placenta: administration of either 800 mcg of misoprostol or placebo 60 minutes after birth of the baby, in absence of postpartum haemorrhage

Eligibility

Inclusion criteria

Inclusion criteria: 1. All women with at least 25 completed pregnancy weeks and retained placenta; 2. At least 18 years of age; 3. Master the Dutch language in word and script.

Exclusion criteria

Exclusion criteria: 1. Excessive blood loss (>1000 ml) within 60 minutes after the delivery of the newborn; 2. Allergy for misoprostol or one of its components.

Design outcomes

Primary

Measure	Time frame
1. Number of spontaneous delivered placentas; 2. Number of manual removals and amount of blood loss.	—

Secondary

Measure	Time frame
1. Interval between delivery of the baby and administration of misoprostol; 2. Interval between administration of misoprostol and delivery of the placenta; 3. Placenta captiva.	—

Contacts

Public ContactGiel Stralen, van

Leiden University Medical Center (LUMC), Department of Gynaecology

G.van_Stralen@lumc.nl

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)