The state of the nervous system, psychology and eyes of HIV-infected children in comparison to healthy children.

Neurological, visual and neurocognitive performance in pediatric HIV‐1‐infected patients as compared to healthy controls.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON20039

Enrollment

Registered

2013-07-12

Start date

2012-12-28

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV, neuropathology, AIDS, children, co-morbidities of antiretroviral therapy

Interventions

None (observational study)

Eligibility

Inclusion criteria

Inclusion criteria: Confirmed HIV-1 infection (cases only) 8-18 years of age

Exclusion criteria

Exclusion criteria: Trauma >30 minutes Intracranial malignancy Severe psychiatric disorders MRI contra-indications

Design outcomes

Primary

Measure	Time frame
Neuropsychological performance MRI/MRS- white matter abnormalities, cerebral perfusion, metabolite concentrations Ophthalmological assessment outcomes Optical Coherence Tomography outcomes	—

Secondary

Measure	Time frame
Cerebrospinal fluid/blood: neuro-damage markers, immune activation markers Antiretroviral therapy concentration in CSF/Blood	—

Contacts

Public ContactS Cohen

Dpt of pediatric infectious diseases Emma Children's Hospital AMC Meibergdreef 9

0205665675

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)