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Thermoregulatory behavior.

Relation between thermo-physiology and behavioral control of body temperature.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON20014
Enrollment
16
Registered
2012-07-12
Start date
2012-05-01
Completion date
Unknown
Last updated
2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thermal behavior, thermal comfort, thermal sensation, physiology

Interventions

Cold and heat exposure during three trials: 1. Protocol A is composed of a neutral-to-warm transition in ambient temperature (24°C to 32°C, with 4 K/h)
2. Protocol B is composed of a neutral-to-cold transition in ambient temperature (24°C to 16°C, with 4 K/h)
3. During protocol C ambient temperature will be varied between three fixed temperatures (16°C, 24°C and 32°C).

Sponsors

Maastricht University Medical Center (MUMC+)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Caucasian healthy females on oral contraceptive; 2. Age: 18 to 30 years; 3. BMI: 20-25; 4. Fat percentage: 20-30%.

Exclusion criteria

Exclusion criteria: 1. Regular medication use; 2. Pregnancy; 3. Hypertension (systolic/diastolic blood pressure >140/90); 4. Hypotension (systolic/diastolic blood pressure <90/60); 5. General feeling of illness at day of experiment; 6. (History of) cardiovascular diseases; 7. In the presence of any known or suspected obstructive disease of the gastrointestinal tract, including but not limited to diverticulitis and inflammatory bowel disease; 8. A history of disorders or impairement of the gag reflex; 9. Previous gastrointestinal surgery; 10. Hypo motility disorders of the gastrointestinal tract including but not limited to Illeus.

Design outcomes

Primary

MeasureTime frame
1. The intention of thermoregulatory behavior, using a questionnaire; 2. Energy expenditure, as measured using indirect calorimetry in a climate controlled respiration chamber.

Secondary

MeasureTime frame
1. Thermal comfort, using a questionnaire with a VAS; 2. Thermal sensation, using a questionnaire with a VAS; 3. Thermal environment, using a questionnaire with a VAS; 4. Skin temperature, using iButtons; 5. Core temperature, using an ingestible pill; 6. Skin perfusion, using Laser Doppler Flowmetry; 7. Blood parameters.

Contacts

Public ContactChristel Jacquot

Universiteitssingel 50

christel.jacquot@maastrichtuniversity.nl+31 (0)43 3884259

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)