Atrial fibrillation, Atriumfibrilleren, Therapy adherence, Therapietrouw, NOAC, DOAC
Conditions
Interventions
None
Sponsors
Leiden University Medical Center
Eligibility
Inclusion criteria
Inclusion criteria: 1. New-onset or recent history of atrial fibrillation, documented as: - 12-lead ECG, or - Holter recording (duration >= 30 seconds), or - Loop recorder or device detected Atrial High-Rate Episode of at least 24 hours 2. Age >= 18 years 3. Able and willing to sign informed consent for the registry
Exclusion criteria
Exclusion criteria: 1. Mechanical heart valve or moderate-to-severe mitral stenosis 2. Life expectancy < 6 months 3. Atrial fibrillation following cardiothoracic surgery within 14 days
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Investigate how daily use (dosing, adherence and persistence) of anticoagulants in patients with NVAF is related to the risk of ischemic stroke, major and clinically relevant non-major bleeding, and (cardiovascular) death. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) determine which patient, doctor and practice characteristics are related to improper use /non-adherence and develop a tool to predict therapy non-adherence and persistence 2) validate and refine an existing bleeding model for NOAC and VKA users and define modifiable risk factors for bleeding. | — |
Contacts
Public ContactM.V. Huisman
Leiden University Medical Center (LUMC) Department of Thrombosis and Haemostasis Room C4-68 P.O Box 9600
Outcome results
None listed