EVALUATION OF DYNAMIC MRI WITH T1-MAPS CORRELATED WITH HISTOPATHOLOGY IN PATIENTS WITH CROHN'S DISEASE.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON19958

Enrollment

Registered

2010-02-04

Start date

2008-12-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Crohn's disease, ziekte van Crohn

Interventions

Preoperative MRI with extra dynamic sequence.

Eligibility

Inclusion criteria

Inclusion criteria: 1. Proven Crohn's Disease (by endoscopy or histopathology); 2. Scheduled to undergo small-bowel surgery for Crohn's Disease.]; 3. Scheduled to undergo a preoperative MRI.

Exclusion criteria

Exclusion criteria: 1. Age < 18 years; 2. General contraindications for MRI (pacemaker, claustrophobia, renal insufficiency and pregnancy).

Design outcomes

Primary

Measure	Time frame
The main study parameter will be the accuracy of detecting disease activity and efficacy of DCE MRI at MR in patients with proven Crohn’s disease as compared to histopathology.	—

Secondary

Measure	Time frame
The secondary study parameters will be the accuracy of detecting disease activity on DCE-MRI as compared to CDAI and CRP. Also the aspect of the bowel wall (serositis or normal) as seen during surgery will be compared to the MRI and the histology.	—

Contacts

Public ContactM.L.W. Ziech

Meibergdreef 9

m.l.ziech@amc.uva.nl+31 (0)20 5663740

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)