E-mental health Depression Anxiety Eye diseases Economic evaluation
Conditions
Interventions
E-PsEYE is a patient-centered, cognitive behavioral therapy (CBT)-based e-mental health intervention, offered via the Internet with digital and telephone guidance of a social worker, for patients with
(2) dealing with retinal diseases and uncertainty surrounding treatment
(3) dealing with depression and anxiety
(4) dealing with fatigue and stress
(5) participating in pleasurable activities
(6) replacing self-defeating thoughts with healthier thoughts
(7) identifying and replacing negative thought patterns
(8) identifying and replacing negative communication styles
and (9) setting goals for the future.
A stepped-care model with three steps will be used to deliver the intervention: (1) offering the first module, i.e. providing information and psycho-education,
Sponsors
VU University Medical Centre
Eligibility
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this study, patients must meet all of the following criteria: (1) they should be 50 years or older; (2) they should be diagnosed with a retinal disease (i.e. macular degeneration, diabetes retinopathy and/or macula oedema); (3) they should be treated with anti-VEGF injections for their retinal disease; (4) they should have at least mild symptoms of depression and/or anxiety (score of 5 or higher on the Patient Health Questionnaire-9, and/or score of 3 or higher on the Hospital Anxiety and Depression Scale – Anxiety); (5) they should be able to speak the Dutch language adequately; (6) they should have access to the Internet.
Exclusion criteria
Exclusion criteria: Patients are excluded from participation in this study when: (1) they are cognitively impaired, which is assessed by telephone with a score < 3 on the six-item Mini Mental State Examination; (2) have a score of 20 or higher on the Patient Health Questionnaire-9, indicating severe symptoms of depression; (3) indicate to be suicidal; (4) are heavy drinkers (score of 8 or higher on the Alcohol Use Disorders Identification Test).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main outcome measures are: (1) depression (Patient Health Questionnaire-9); (2) anxiety (Hospital Anxiety and Depression Scale – Anxiety) (3) quality-adjusted life-years (determined with the Health Utility Index-3 and the Euroqol 5-Dimensions). | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary clinical outcomes are: (1) adaptation to vision loss (Adaptation to Vision Loss scale); (2) illness-cognitions (Illness Cognition Questionnaire); (3) vision-related quality of life (Low Vision Quality of Life questionnaire); (4) mastery (Pearlin Mastery Scale); (5) cognitive therapy skills (Competencies of Cognitive Therapy Scale-Self Report). Cost-evaluation outcomes are: (1) health care utilisation (iMTA Medical Consumption Questionnaire); (2) absence and presenteeism from work (iMTA Productivity Cost Questionnaire). Process evaluation outcomes are: (1) compliance; (2) recall; (3) patient satisfaction (Dutch Mental Healthcare thermometer); (4) therapist satisfaction. During the trial, a qualitative problem analysis study on barriers and facilitators for implementation will be conducted to identify and target barriers for nationwide implementation. | — |
Contacts
Public ContactH.P.A. Aa, van der
De Boelelaan 1117
Outcome results
None listed