Benign Prostate Obstruction/Hyperplasia who are eligible for an TURP
Conditions
Interventions
Patients will be randomized in either:
Group A: Who will undergo a bipolar TURP or in
Group B: who will undergo a monopolar TURP.
Sponsors
Academic Medical Center, Department of Urology
Eligibility
Inclusion criteria
Inclusion criteria: 1. Candidates foor TURP; 2. Qmax 14; 4. Voided volume > 125; 5. Patients in retention with an indwelling catheter or intermittent catheterisation; 6. Given informed consent.
Exclusion criteria
Exclusion criteria: 1. Suspected from prostate cancer; 2. Prior prostate surgery, including minimal invasive therapies; 3. Active urinary tract infection; 4. Known or suspected neurogenic decompensated bladder (PVR>400ml/sec) or compensated detrusor function; 5. Immunosuppression; using prednisone; 6. Known or suspected malignant disease affecting the bladder or lower urinary tract; 7. 5-alpha-reductase inhibitor within the last 3 months before baseline; 8. Alpha-blockers within the last 6 weeks before baseline; 9. Specific severe heart disease in whom anti-coagulant therapy might jeopardize treatment outcome.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Safety bipolar TURP compared with monoploar TURP by means of TUR syndrome, blood loss, number and severity of adverse events. | — |
Secondary
| Measure | Time frame |
|---|---|
| Efficacy bipolar TURP compared with monopolar TURP by means of IPSS/QoL-scores, IIEF-score, Qmax, cutting rate, length of catherisation, lenght of hospital stay, length of operation, impact on PSA level, number of strictures. | — |
Contacts
Public ContactS.A. Zaaijer
Academic medical Center (AMC) Department of Urology P.O. Box 22660
Outcome results
None listed