Symptomatic Irreversible Pulpitis and Symptomatic Apical Periodontitis
Conditions
Keywords
Ultrasonic, Diode laser, Irrigation, Activation
Brief summary
The study is designed to determine whether activation of the irrigant using ultrasonic or diode laser technology can reduce postoperative pain and influence Substance P levels compared with conventional needle irrigation. The findings may contribute to establishing evidence-based irrigation activation protocols for improving patient comfort following root canal treatment.
Interventions
PROCEDUREdiode laser activation irrigation
This group will receive diode laser-activated irrigation using a 940-nm diode laser (Epic X, BIOLASE).
PROCEDUREUltrasonic irrigation activation
This group will receive ultrasonic-activated irrigation using the Ultra X ultrasonic activation device (Eighteeth).
Sponsors
October 6 University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
Inclusion 1. Healthy patients ranging between 18 and 65 years in age . 2. Patients that experienced moderate-to-severe pain (4-10)-represented on a visual analogue scale (VAS). 3. Having a mandibular single rooted premolar tooth with vital pulp. 4. Having the symptoms of symptomatic irreversible pulpitis and apical periodontitis. Exclusion 1. Patients who were pregnant or lactating. 2. Patients taking analgesic or anti-inflammatory drugs within the least 12 hours. 3. Teeth with calcified root canals, resorptions. 4. Previously root canal treated. 5. severe damage and associated traumatic occlusion. 6. Teeth with open apices. 7. Presence of periodontal pockets \>3 mm in the affected tooth.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative pain | 12,24,48 hours | Postoperative pain will be assessed using a Visual Analog Scale (VAS) following conventional root canal treatment. Pain will be recorded at baseline before treatment and at predetermined postoperative time points to compare pain levels among the conventional needle irrigation, ultrasonic-activated irrigation using Ultra X, and 940-nm diode laser-activated irrigation using Epic X groups. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Substance P level | up to 24 hours | Substance P levels will be measured using an enzyme-linked immunosorbent assay (ELISA) to evaluate the effects of conventional needle irrigation, ultrasonic-activated irrigation using Ultra X, and 940-nm diode laser-activated irrigation using Epic X on Substance P levels. Measurements will be performed at the time points specified in the study protocol, and the results will be compared among the three study groups. |
Countries
Egypt
Contacts
CONTACTAlaa Hani Omaria, Master degree candidate
CONTACTMohsen Abielhasan, Dean
Outcome results
None listed