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Comparing the Efficacy of a Conversational Agent (QuitBot) Versus Standard Health Education on Smoking Cessation Among Medical Students; A Randomized Controlled Trial.

Comparing the Efficacy of a Conversational Agent (QuitBot) Versus Standard Health Education on Smoking Cessation Among Medical Students; A Randomized Controlled Trial.

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07906249
Enrollment
180
Registered
2026-10-30
Start date
2026-12-10
Completion date
2027-12-31
Last updated
2026-10-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Conversational Agent, Smoking Cessation

Keywords

Smoking cessation

Brief summary

Comparing the efficacy of conversational agent and standard health education in promoting smoking cessation among medical students in Cairo university

Detailed description

Tobacco smoking remains one of the leading causes of preventable morbidity and mortality worldwide, accounting for more than 8 million deaths annually (world health organization, 2023). Smoking among medical students represents a critical paradox in public health. As future physicians, they are expected to be role models and champions of preventive health, yet global studies indicate a persistent and concerning prevalence of tobacco use within this group, with rates varying from 5% to over 30% in different regions (AlSairafi & AlKandari, 2023). In Egypt, the situation is particularly pressing; a recent systematic review estimated the pooled prevalence of smoking among medical students to be approximately 18.5%, with some studies reporting rates as high as 28% among males (El-Masry et al., 2023). This high prevalence is often attributed to intense academic stress, social factors, and the normalization of smoking in certain environments (Bassiony et al., 2015). This behavior undermines their personal health and future professional credibility and effectiveness in tobacco cessation counseling Digital health technologies have emerged as effective and scalable tools for behavior change interventions. Mobile applications, web-based programs, and short message service (SMS) based interventions have demonstrated modest but significant effects on smoking cessation outcomes (whittaker et al., 2019). Among these digital approaches, conversational agents, or chatbots, offer unique advantages through real-time, interactive, and personalized communication (abdullah et al., 2023). Chatbots simulate human conversation and can provide continuous motivational and cognitive-behavioral support using natural language processing algorithms. Their 24/7 availability, anonymity, and ability to tailor responses based on user input make them highly suitable for youth and young adults who are digitally literate and familiar with online interaction (prochaska et al., 2021). So, This study hypothesizes that medical students who smoke and receive the combined intervention of the "QuitBot" conversational agent plus an evidence-based cessation guidelines will demonstrate a statistically significant higher rate of day point prevalence smoking abstinence and prolonged abstinence at 1 and 3months respectively post-intervention, compared to those who receive the evidence-based handbook alone. Since many similar studies have been conducted in high-income countries, there is very limited evidence from low- and middle-income contexts such as Egypt (el-amin et al., 2021). Medical students in Egypt are an ideal population for testing the feasibility of such a digital intervention, given their high rates of smartphone ownership and social media use. So, implementing quitbot among medical students could provide valuable insights into the acceptability, usability, and effectiveness of chatbot-based smoking cessation tools. Furthermore, this approach aligns with the global public health objective of integrating artificial intelligence-driven behavioral interventions into preventive healthcare strategies (world health organization, 2023).

Interventions

Conversational Agent Behavioral Participants use an AI-powered conversational chatbot for smoking cessation support

Standard health education according to USPSTF guidelines

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Intervention model description

Participants receive access to the quitbot conversational Chabot. "QuitBot" an AI-powered conversational chatbot app designed to help individuals quit smoking,

Eligibility

Sex/Gender
ALL
Age
19 Years to 24 Years
Healthy volunteers
No

Inclusion criteria

* Enrolled adult medical student at Cairo University with age range (19 - 25) years old. The age range will be from 19 years old to fulfill WHO definition of adulthood. * Current smoker (defined as smoking at least one cigarette- cigarette or vaping per day in the past month). * Motivated to quit smoking within the next six months. * Able to communicate in English sufficiently to use the chatbot. * Has access to a smartphone with internet connection. * Provides informed consent to participate.

Exclusion criteria

* Students currently enrolled in another smoking cessation program or using pharmacological cessation aids. * Students with known severe psychiatric illness or cognitive impairment that may interfere with chatbot interaction identified by self-report. * Students unable or unwilling to provide consent.

Design outcomes

Primary

MeasureTime frameDescription
Comparing the effectiveness of the quitbot conversational chatbot in promoting smoking cessation versus traditional cessation education among medical students in Cairo University3 monthsVarying cessation by direct asking after 3 months

Secondary

MeasureTime frameDescription
To determine User satisfaction, feasibility and usability score. To evaluate the perceived effectiveness of the chatbot in promoting smoking cessation among the intervention group.3 monthsConversational agent arm will fill a questionnaire to determine satisfaction, feasibility and usability Both arm will fill a qutionaaire for perceived effectiveness

Countries

Egypt

Contacts

CONTACTDoha Ramadan Mahmoud, Msc degree in family medicine
doharamadan5782@gmail.com01019164696

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Oct 31, 2026