Laparoscopic Cholecystectomy, Postoperative Pain
Conditions
Keywords
Laparoscopic cholecystectomy, Transversus abdominis plane block, Recto-intercostal fascial plane block
Brief summary
Laparoscopic cholecystectomy is commonly associated with moderate postoperative pain, particularly during the early postoperative period. Inadequate postoperative analgesia may negatively affect patient comfort and recovery, increase opioid consumption, and contribute to opioid-related adverse effects. Therefore, effective multimodal analgesic strategies are of considerable importance in patients undergoing laparoscopic cholecystectomy. Subcostal transversus abdominis plane (TAP) block is a regional anesthesia technique used to provide analgesia for upper abdominal surgery. However, its analgesic coverage may be insufficient in some patients because of the complex innervation of the upper abdominal wall. The recto-intercostal fascial plane block has been described as a fascial plane block targeting the anterior branches of the thoracoabdominal nerves and may provide additional analgesic benefit when combined with subcostal TAP block. This study aims to compare the postoperative analgesic efficacy of bilateral subcostal TAP block alone with that of bilateral subcostal TAP block combined with recto-intercostal fascial plane block in patients undergoing elective laparoscopic cholecystectomy.
Interventions
Following induction of general anesthesia and before surgical incision, a bilateral ultrasound-guided subcostal transversus abdominis plane block will be performed using a total volume of 40 mL of 0.20% bupivacaine.
Following induction of general anesthesia and before surgical incision, a bilateral ultrasound-guided recto-intercostal fascial plane block will be performed using a total volume of 30 mL of 0.20% bupivacaine.
Sponsors
Diskapi Yildirim Beyazit Education and Research Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Age between 18 and 80 years * With a body mass index (BMI) between 18 and 30 kg/m². * American Society of Anesthesiologists (ASA) physical status I, II, or III * Scheduled to undergo elective laparoscopic cholecystectomy
Exclusion criteria
* Age younger than 18 years or older than 80 years * With a body mass index (BMI) below 18 or above 30 kg/m² * American Society of Anesthesiologists (ASA) physical status IV or higher
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pain Score | At 6 hours after surgery. | Pain will be assessed at rest using the visual analog scale on a scale from 0 (no pain) to 100 (worst pain). Pain assessment will be done at 6th hour after surgery. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pain Scores | At 0, 1, 2, 12, and 24 hours after surgery. | Pain will be assessed at rest using the visual analog scale on a scale from 0 (no pain) to 100 (worst pain). Pain assessment will be done at 0st, 1st, 2nd, 12th, and 24th hours after surgery. |
| Total Postoperative Opioid Consumption During the First 24 Hours After Surgery | During the first 24 hours after surgery. | Total Postoperative Opioid Consumption During the First 24 Hours After Surgery |
Countries
Turkey (Türkiye)
Contacts
CONTACTElif Şule Özdemir Sezgi
CONTACTAslı Dönmez
Outcome results
None listed