Rigid Bronchoscopy Ventilation
Conditions
Brief summary
This study compares the effects of different ventilation strategies on patient safety and respiratory parameters during rigid bronchoscopy procedures. It enrolls patients undergoing the procedure at Qingdao University Affiliated Hospital, aiming to identify the optimal ventilation mode to reduce complications.
Interventions
PROCEDUREJet Ventilation
Jet ventilation delivered throughout rigid bronchoscopy procedure
PROCEDURESpontaneous Assisted Ventilation
Spontaneous assisted ventilation applied during rigid bronchoscopy to preserve patients' spontaneous breathing
Sponsors
The Affiliated Hospital of Qingdao University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients scheduled for elective interventional rigid bronchoscopy, who agree to participate in this study and have no contraindications to anesthesia.
Exclusion criteria
* History of allergic reaction to anesthetic agents; * Pregnancy; * Severe dysfunction of the heart, lung, liver, kidney or other vital organs; * Cognitive impairment or neurological diseases; * Contraindications to succinylcholine (e.g., hyperkalemia, extensive burns, severe trauma, crush injury, spinal cord injury, paraplegia, hemiplegia, myasthenia gravis, etc.); Refusal to participate in this study by the patient or their family members.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| peripheral oxygen saturation | From enrollment to study completion, continuous monitoring during the entire observation period | Use pulse oximetry to continuously monitor and record peripheral oxygen saturation (SpO₂) values throughout the study period, to evaluate the incidence and duration of hypoxemia. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| arterial blood pH | Measurements will be performed 10 minutes after initiation of each respective ventilation mode. | Collect arterial blood pH values by arterial blood gas analysis to assess the acid-base status of subjects. |
| arterial partial pressure of carbon dioxide | 10 minutes after initiation of each ventilation mode | Collect arterial partial pressure of carbon dioxide (PaCO₂) via arterial blood gas analysis. |
Countries
China
Contacts
CONTACTXiangyu Ji
Outcome results
None listed