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Optimizing Chatbot Reminder Timing in a Chatbot Cessation Service: A Micro-Randomized Trial

A Micro-Randomized Trial to Optimize the Timing of Weekly Chatbot Reminders for User Engagement in a Chatbot Cessation Service

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07826884
Enrollment
350
Registered
2026-09-17
Start date
2026-09-28
Completion date
2027-12-31
Last updated
2026-09-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Smoking Cessation

Keywords

Smoking cessation, Behavioral counselling, Digital health, Artificial intelligence, Chatbot, Engagement, Push notification

Brief summary

The goal of this study is to learn whether the timing of weekly chatbot reminders affects user engagement with the chatbot cessation service. Participants enrolled in the routine chatbot cessation service will be included in a micro-randomized trial. The delivery timing of weekly reminders will be randomly assigned across different day types and times of day during the 12-week chatbot cessation service period. The study will use routine chatbot system records to evaluate engagement after reminder delivery, including whether participants respond to the chatbot and how quickly they re-engage with the service.

Detailed description

Sustained user engagement remains a challenge in digital smoking cessation interventions. In this chatbot cessation service, routine weekly AI-generated reminders are used to encourage users to re-engage with chatbot-based smoking cessation support during the 12-week service period. However, the optimal timing for delivering these reminders remains uncertain. This study is an embedded micro-randomized trial conducted within the existing chatbot cessation service. The aim of this study is to evaluate whether the timing of weekly chatbot reminders influences short-term user engagement and to identify optimal reminder delivery schedules. Participants enrolled in the routine chatbot cessation service will be included in the micro-randomized trial through an opt-out approach. The trial will not introduce any additional intervention components, measurements, or study visits beyond the existing chatbot cessation service and follow-up assessments. Participation in the micro-randomized trial will only affect the timing of routine weekly reminders. During the 12-week chatbot cessation service period, excluding the initial welcoming message, the delivery timing of 11 weekly reminders will be randomized across predefined day-type and time-of-day conditions. Reminder strategy will remain unchanged. The primary proximal outcome is meaningful engagement with the chatbot within 24 hours after reminder delivery, as recorded by the chatbot system. Secondary outcomes include reply status, response latency, and meaningful engagement within 48 and 72 hours after reminder delivery. Meaningful engagement is defined as user messages relevant to smoking cessaation. The findings from this study will provide evidence to optimize the timing of routine chatbot reminders and inform future development of optimized reminder strategies and adaptive digital smoking cessation interventions.

Interventions

BEHAVIORALChatbot Cessation Service With Randomized Reminder Timing

The chatbot cessation service provides digital smoking cessation support through a chatbot platform. Participants receive routine chatbot-based cessation support, including scheduled weekly AI-generated reminders during the 12-week service period. Excluding the initial welcoming message, the timing of the remaining 11 weekly reminders will be repeatedly randomized at weekly decision points across predefined day-type and time-of-day conditions. The randomized component is limited to reminder delivery timing. All participants receive the same chatbot content and support.

Sponsors

The University of Hong Kong
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Intervention model description

An embedded micro-randomized trial within the chatbot cessation service. Participants will remain in a single chatbot cessation service cohort and will be repeatedly randomized at each weekly decision point to receive scheduled reminders delivered under predefined day-type (weekday/weekend) and time-of-day (morning/afternoon/evening) conditions during the 12-week chatbot cessation service period.

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Able to communicate in Chinese (Cantonese) * Have access to or are willing to use WhatsApp to access the chatbot cessation service * Used any tobacco in the past 30 days (including all types of tobacco products such as cigarette, shisha, electronic cigarettes, and heat-not-burn (HNB))

Exclusion criteria

* Have communication difficulties (either physical or cognitive) that prevent completion of the counselling and assessments * Having queries irrelevant to tobacco control

Design outcomes

Primary

MeasureTime frameDescription
Meaningful engagement with chatbot within 24 hours after reminder deliveryWithin 24 hours after each randomized reminder delivery during the 12-week chatbot cessation service periodMeaningful engagement is defined as any reply regarding smoking cessation excluding emoji and simple message like "Hi" within 24 hours after receiving a randomized weekly reminder. Engagement will be automatically recorded by the chatbot system.

Secondary

MeasureTime frameDescription
Any chatbot reply within 24 hours after reminder deliveryWithin 24 hours after each randomized reminder delivery during the 12-week chatbot cessation service periodWhether participants provide any reply to the chatbot after receiving a randomized weekly reminder, as recorded by the chatbot system.
Response latency after reminder deliveryWithin 72 hours after each randomized reminder delivery during the 12-week chatbot cessation service periodThe time interval between randomized reminder delivery and the participant's first reply to the chatbot within 72 hours after reminder delivery, as recorded by the chatbot system.
Extended meaningful engagement with chatbot after reminder deliveryWithin 48 and 72 hours after each randomized reminder delivery during the 12-week chatbot cessation service periodMeaningful engagement is defined as any reply regarding smoking cessation excluding emoji and simple message like "Hi" within 48 and 72 hours after receiving a randomized weekly reminder. Engagement will be automatically recorded by the chatbot system.

Countries

Hong Kong

Contacts

CONTACTMan Ping Wang
mpwang@hku.hk+852 3917 6636

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 18, 2026