Obese or Overweight Healthy Volunteers
Conditions
Keywords
Intermittent fasting, Time-restricted feeding, Obesity, Body composition, ALT, Exercise, Randomized controlled trial.
Brief summary
This study was conducted to compare the effects of a 12-week 16:8 Time-Restricted Feeding (Intermittent Fasting) + home-based exercise protocol with and a calorie-restricted Standard Diet (SD) + home-based exercise protocol on body composition, lipid profile, glycemic control, and liver function enzyme levels in obese women.
Interventions
OTHER16:8 Time-Restricted Feeding and Exercise
Participants followed a 16:8 time-restricted feeding protocol (fasting for 16 hours and consuming all daily caloric intake within an 8-hour window) combined with a structured home-based exercise program for 12 weeks.
OTHERStandart Diet and Exercise
Participants followed a standard energy-restricted diet distributed across regular daily meals combined with a structured home-based exercise program for 12 weeks
Sponsors
TC Erciyes University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
45 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
1. Body Mass Index between 30 and 40 2. Female 3. Agreeing to adhere to a calorie-restricted diet 4. Agreeing to adhere to an exercise program
Exclusion criteria
1. Having cancer, diabetes, or thyroid disease 2. Having received assistance with weight loss in the last 3 months 3. Inability to adhere to calorie restriction 4. Failure to adhere to an exercise program
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes in Glucose Metabolism, Lipid Profile, and Liver Enzymes | Baseline and 12 weeks | Evaluation of changes in glucose metabolism (fasting glucose, fasting insulin, HOMA-IR), lipid profile (total cholesterol, HDL, LDL, triglycerides), and liver function enzymes (ALT, AST) from baseline to the end of 12 weeks. |
Countries
Turkey (Türkiye)
Outcome results
None listed