HCC - Hepatocellular Carcinoma, Quality of Life, Self-care, TACE(Transcatheter Arterial Chemoembolization), Transarterial Chemoembolization, Web-based Intervention
Conditions
Brief summary
This randomized controlled trial aims to evaluate the effectiveness of enhanced web-based health education on self-care practices and quality of life among patients with hepatocellular carcinoma. A total of 252 participants undergoing transarterial chemoembolization (TACE) will be randomly assigned to an intervention group or a control group. The intervention group will receive routine health education combined with enhanced web-based health education, while the control group will receive routine health education and printed educational materials. Knowledge, self-care practices, and quality of life will be assessed at baseline, 1 month, and 3 months after TACE. The study will determine whether enhanced web-based health education can improve self-care practices and quality of life in patients with hepatocellular carcinoma undergoing TACE.
Interventions
BEHAVIORALEnhanced Web-Based Health Education
Participants in the intervention group will receive routine health education combined with an enhanced web-based health education program designed to support self-care among patients with hepatocellular carcinoma undergoing TACE. The web-based program provides educational content on hepatocellular carcinoma and TACE, preparation for TACE, post-TACE care, management of common symptoms, nutrition, medication adherence, warning signs, follow-up care, and self-care practices. Educational information is delivered through written materials, images, and videos and can be accessed by participants during the study period.
BEHAVIORALRoutine Health Education
Participants in the control group will receive routine health education and printed educational materials according to usual care for patients undergoing TACE.
Sponsors
University Medical Center Ho Chi Minh City (UMC)
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Intervention model description
Participants will be randomly assigned in a 1:1 ratio to either the intervention group or the control group. Both groups will be followed in parallel, with outcomes assessed at baseline, 1 month, and 3 months after TACE.
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* • Patients aged 18 years or older who are diagnosed with hepatocellular carcinoma (HCC) and are scheduled to undergo Transarterial Chemoembolization (TACE) for the first time at the Department of Hepatobiliary and Pancreatic Surgery, University Medical Center Ho Chi Minh City. * Patients who agree to participate in the study and provide informed consent.
Exclusion criteria
* • Patients with HCC scheduled to undergo TACE who have diagnosed cognitive impairment due to neurological disorders. * Patients who are unable to understand spoken Vietnamese. * Patients with language or hearing impairments that interfere with communication and participation in the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Knowledge Score | Baseline, 1 month, and 3 months after TACE | Knowledge will be assessed using a 17-item researcher-developed questionnaire. Higher scores indicate better knowledge. The instrument was evaluated for content validity and demonstrated high internal consistency, with a Cronbach's alpha of 0.93. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in Self-Care Practice Score | Baseline, 1 month, and 3 months after TACE | Self-care practices will be assessed using a 15-item researcher-developed questionnaire. Each item is rated on a 5-point Likert scale, with higher scores indicating better self-care practices. The instrument was evaluated for content validity and demonstrated acceptable internal consistency, with a Cronbach's alpha of 0.72. |
Countries
Vietnam
Outcome results
None listed