Menopause Hot Flashes
Conditions
Brief summary
This study is evaluating the effects of cooling on menopausal hot flashes in midlife women. Precise targeted cooling is provided to areas of the skin when a hot flash occurs.
Interventions
OTHERIntervention C (Targeted skin cooling)
Cooling targeted to the skin during a hot flash
OTHERIntervention B (Ambient cooling)
Cooling of the room
OTHERIntervention A (Room temperature)
Control condition (room temperature)
Sponsors
SRI International
National Institute on Aging (NIA)
Stanford University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
NONE
Intervention model description
There are three temperature interventions, each participant may be exposed to during the study: room temperature, ambient cooling, targeted skin cooling
Eligibility
Sex/Gender
FEMALE
Age
40 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Female * Age range: 40 to 65 years and in menopausal transition or post-menopause; * At least 8 years of education to ensure adequate reading proficiency; * Primary language is English or Spanish.
Exclusion criteria
* History of medical or neurological illness or trauma that would affect the central nervous system (e.g., stroke, multiple sclerosis, epilepsy); * Current severe medical conditions (e.g. Diabetes, cancer, cardiovascular disease, renal or hepatic disease, thyroid disorders); * History of schizophrenia and/or bipolar disorder; * Dependence or abuse of illicit substances in the past year; * Current use of hormone therapy or other treatments for hot flash symptoms
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of hot flashes | Across the ~5 hour experimental period in the lab | Number of hot flashes, based on sternal skin conductance measurement |
Countries
United States
Outcome results
None listed