Papillary Thyroid Carcinoma, Thyroid Cancer
Conditions
Keywords
papillary thyroid carcinoma, thyroidectomy, neck dissection, surgical outcomes, clinicopathological pattern
Brief summary
The aim of this study is to evaluate the clinicopathological pattern and surgical outcome of papillary thyroid carcinoma (PTC) at Sohag University Hospitals. This will help improve local risk stratification, optimize surgical decision-making, and guide future management strategies for patients with PTC in this region.
Detailed description
Papillary thyroid carcinoma (PTC) is the most common histological subtype of thyroid cancer, representing about 80-85% of cases. This study is a case-series study with both retrospective (June 2023 - June 2026) and prospective (June 2026 - March 2027) components, conducted at the Department of General Surgery, Sohag University Hospitals. All patients diagnosed with papillary thyroid carcinoma and managed at Sohag University Hospitals during the study period will be included. Data collection includes baseline demographic and clinical features, preoperative laboratory tests (thyroid function tests and serum calcium), neck ultrasonography findings (ACR TI-RADS category, nodule size, and lymph node assessment), fine-needle aspiration cytology (Bethesda System), surgical intervention types (hemithyroidectomy, total thyroidectomy, and neck dissection), final histopathological characteristics (tumor size, multifocality, lymphovascular invasion, extrathyroidal extension, and nodal status), and early postoperative complications (hypocalcemia, recurrent laryngeal nerve palsy, hematoma, seroma, and wound sepsis).
Interventions
None listed
Sponsors
Sohag University
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* All patients diagnosed with papillary thyroid carcinoma and its variants managed at Sohag University Hospitals. * Confirmation of diagnosis histopathologically. * Availability of sufficient clinical, radiological, operative, and pathological data for analysis.
Exclusion criteria
* Patients diagnosed with other types of thyroid malignancy (e.g., follicular, medullary, or anaplastic carcinoma). * Patients with a history of previous thyroid surgery before presentation to the study setting. * Patients with incomplete essential medical records that prevent confirmation of diagnosis or extraction of main study variables.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Prevalence of Extrathyroidal Extension in Papillary Thyroid Carcinoma | 9 months | Percentage of participants with histologically confirmed extrathyroidal extension. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of Early Postoperative Surgical Complications | 9 months | Percentage of participants experiencing early postoperative complications including hypocalcemia, recurrent laryngeal nerve palsy, hematoma, seroma, or wound sepsis. |
| Incidence of Multifocal Papillary Thyroid Carcinoma | 9 months | Percentage of participants found to have multifocal tumors on final histopathological examination. |
| Rate of Cervical Lymph Node Metastasis | 9 months | Percentage of participants with histopathologically confirmed cervical lymph node metastasis. |
Contacts
CONTACTAhmed Aboulabed Resident Ahmed Aboulabed Ahmed Mousa, resident
Outcome results
None listed