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Impact of Sedation Practices on Clinical Outcomes Among Mechanically Ventilated Children

Impact of Sedation Practices on Clinical Outcomes Among Mechanically Ventilated Pediatric Intensive Care Unit Patients

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07821268
Acronym
ISPMVC
Enrollment
30
Registered
2026-09-15
Start date
2026-09-01
Completion date
2027-06-01
Last updated
2026-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mechanically Ventilated Children Admitted to the Pediatric Intensive Care Unit

Keywords

Sedation, pediatric intensive care unit, mechanically ventilated pediatric

Brief summary

evaluate the impact of sedation adequacy on clinical outcomes in mechanically ventilated children admitted to the pediatric intensive care unit (PICU).

Detailed description

evaluate the impact of sedation adequacy on clinical outcomes in mechanically ventilated children admitted to the pediatric intensive care unit (PICU). Sedation is fundamental in the Paediatric Intensive Care Unit (PICU) for mechanically ventilated children, seeking to improve their clinical outcome, enhance ventilator synchronisation, and promote tolerance of invasive procedures. Achieving appropriate sedation is hard, since both under-sedation and over-sedation are linked to negative outcomes, including extended mechanical breathing, heightened risk of ventilator-associated pneumonia

Interventions

OTHERno need

no need

Sponsors

Yasmine Ahmed Abdelrahman
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
0 Years to 18 Years
Healthy volunteers
No

Inclusion criteria

* Children admitted to PICU requiring invasive mechanical ventilation (MV) ≥ 48 hours and received any form of sedation or analgesia during ventilation ≥ 48 hours.

Exclusion criteria

\- children ventilated after cardiac arrest

Design outcomes

Primary

MeasureTime frameDescription
The Richmond Agitation-Sedation Scale (RASS)1 yearis a validated 10-point clinical tool used in PICUs to assess patient alertness, agitation, and sedation depth in \<20 seconds. In your sedation-outcome study, nurses score RASS every 4-8 hours to classify adequate sedation (target: RASS -2 to 0) vs. under-sedation (\>0) or over-sedation (≤-3)

Countries

Egypt

Contacts

CONTACTyasmeen Ahmed abdelrhman
Yassmin.Abdelrahman@med.sohag.edu.eg01289750281

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 16, 2026