Depressive Disorder
Conditions
Keywords
Depression, Aerobic exercise, Antidepressant therapy, Psychotherapy, Beck Depression Inventory (BDI)
Brief summary
The goal of this study is to compare the reduction in the severity of depression after a duration of 06 weeks between patients receiving conventional therapy (antidepressant; Sertraline) only and those receiving both conventional therapy and a structured aerobic exercise (cycling, brisk walking).
Detailed description
This study will compare two groups A and B for 06 weeks to study the reduction in severity of depression. * Comparison group (Group-A): In this group participants will receive standard antidepressant treatment such as Sertraline (SSRIs) and psychotherapy (CBT) only. After 06 weeks, patients will again be assessed for their level of depression using the BDI scale. * Experimental group (Group-B): In this group participants will undergo structured exercise program in addition to conventional pharmacotherapy and psychotherapy. They will be introduced to aerobic exercises which includes cycling and brisk walking and will undergo three supervised sessions for 35 minutes each, per week for total 06 weeks under supervision of trainee psychiatry.
Interventions
BEHAVIORALStructured Aerobic exercise
Participants will receive structured, supervised aerobic exercise ( cycling, brisk walking), in addition to conventional treatment consisting of 03 sessions per week, 35 minutes each for 06 weeks.
Sponsors
Manahil Gill
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Intervention model description
RCT
Eligibility
Sex/Gender
ALL
Age
18 Years to 55 Years
Healthy volunteers
No
Inclusion criteria
i. All new patients diagnosed with moderate and severe depression using BDI scale according to ICD-11 criteria between the ages of 18-55 years. ii. Both genders will be included.
Exclusion criteria
i. Patients with severe physical disabilities such as Spinal cord injuries, severe osteoporosis or medical conditions that prevent exercise such as ischemic changes in ECG pre-exercise. ii. Pregnant females. iii. Individuals already engaging in physical activities like athletes.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Beck Depression Inventory (BDI) score | Baseline to 06 weeks | The primary outcome will be the mean change in Beck Depression Inventory (BDI) score from baseline to the end of 06 weeks intervention period. It is a 21- item self-report scale with total scores ranging from 0 to 63. Lower scores indicate fewer depressive symptoms and therefore a better outcome. The mean change in BDI score will be compared between the aerobic exercise (plus conventional treatment ) group and the non exercise group. (conventional treatment only). |
Countries
Pakistan
Contacts
CONTACTManahil Gill, MBBS
CONTACTMuhammad Ahsan Mustafa, MBBS
Outcome results
None listed