Rural Water Filtration and Health Study

Diarrhea, Enteric Pathogens, Gastrointestinal Disease, Waterborne Diseases

Acute Gastrointestinal Illness, Central Appalachia, Cluster Randomized Controlled Trial, Diarrhea, Drinking Water Contamination, Enteric Pathogens, Intervention Trial, Point-of-Use Water Treatment, Rural Health, Spring Water, Water Filtration, Waterborne Diseases, Well Water

The goal of this intervention trial is to learn if the use of drinking water filters will result in improved health outcomes for people living in homes with well water and spring water in rural regions of Central Appalachia.

Consumption of unsafe drinking water is associated with a substantial burden of disease. Tens of millions of people in the United States live in homes with unregulated private wells, primarily in rural regions. However, our understanding of drinking water contaminants and associated health impacts for individuals living in households with private water supply in rural areas of the United States is severely limited by a lack of data - particularly for individuals living in low-income households in rural areas of Appalachia, and in the Central Appalachia region especially. The overarching goal of this study is to assess the potential of a household-level water treatment intervention for expanding safe water access and improving health outcomes and wellbeing for rural households without utility-supplied water. Investigators will enroll approximately 480 households (approximately 1,600 individuals) that use well water and spring water and conduct a cluster-randomized controlled trial in southwest Virginia and northeast Tennessee to evaluate the hypothesized benefits of point-of-use water filtration. Investigators will undertake the following aims: 1. Measure the effect of drinking water filtration on the incidence of reported acute gastrointestinal illness. 2. Measure the effect of drinking water filtration on the presence and quantity of bacterial, protozoal, and viral pathogens detected in saliva and stool biospecimens. 3. Quantify fecal indicator organisms, waterborne pathogens, and regulated chemical contaminants in drinking water samples. This study was designed to rigorously assess the hypothesized benefits of a relatively low-cost and easy to use point-of-use water treatment approach that can also improve the taste of water, and is a less-costly alternative to bottled water. Findings from this study will also substantially improve our understanding of which waterborne and enteric pathogens infants, children, and adults living in households with private water supplies in rural areas of Central Appalachia are exposed to and infected with, enabling more informed estimates of the associated burden of disease for rural populations without utility-supplied water.

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