Depressive Disorder
Conditions
Brief summary
This is a retrospective observational study based on our hospital's prospective peri-operative elderly patient database. We aim to evaluate the correlation between the 9-item Patient Health Questionnaire (PHQ-9) and the brief 3-item Patient Health Questionnaire (PHQ-3) for screening depressive symptoms among elderly surgical patients. Secondary outcomes include the associations of the two scales with adverse events: 30-day post-operative mortality, readmission, surgical site infection, delirium, and 1-year all-cause mortality. No additional interventions will be performed; only existing routinely-collected clinical data will be analysed.
Interventions
No trial-specific intervention. This study is a secondary analysis of existing routine clinical data including PHQ-3 and PHQ-9 scores.
Sponsors
Chinese PLA General Hospital
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* 1\. Aged ≥ 65 years old 2. Patients undergoing surgery under general anesthesia
Exclusion criteria
* 1\. ASA physical status ≥ IV (including ASA class IV) 2. Patients transferred to the intensive care unit (ICU) after surgery 3. Preoperative history of schizophrenia, epilepsy, or Parkinson's disease 4. Diseases requiring corticosteroid therapy for more than 7 days within 1 year before surgery 5. Preoperative inability to communicate (coma, severe dementia, or language/hearing impairment), or MMSE score \< 26 6. Any cerebrovascular event within the past 3 years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1-year all-cause mortality after surgery | 12 months after surgery |
Countries
China
Outcome results
None listed